Socioeconomic trends indicate that our society is postponing having children until much later in the parents life.
However, the biological clock continues to move forward; the quality of oocytes and sperm continuously decrease. The newest opportunities of cell and tissue cryopreservation are so gentle that they allowfor the thawing and usage for conception purposes even after a decade of storage in the cryobank.
Cryopreservation means the freezing of cells in liquid nitrogen at temperatures that can reach –196°C. Typically during the freezing process, the water contained in cells turns into ice crystals, which cause cell damage. The newest freezing technique used at Unica is called Cryotop. This technique has proven to be a very effective method of freezing and thawing cells. Statistics show that this method leaves up to 95% of the frozen cells in perfect condition when thawed.
The most recent studies indicate that the length of frozen egg and sperm preservation by no means influences their condition or quality. Even after long-term placement in the cryobank, high fertility potential is maintained. This is proven by many clinical examples in which live births were achieved after over twenty-years of preservation of reproductive cells.
Today, results show that with the use of the newest cryopreservation methods are even comparable to fresh cells.
- In women: age, weight (BMI), smoking, Anti-Müllerian hormone level (AMH), vitamin D level, alternatively DHEA and antral follicle count (AFC) via an ultrasound.
- In men: complete sperm analysis, sperm quality after 24 hours, and hormonal levels.
- Test results and probability of conception are communicated to patients and a suitable course of action recommended accordingly.