A specialized team of physicians of our clinic has been employing donated oocytes as part of the infertility treatment since the end of the 1990s and builds on a long-term experience with the programme of oocyte donation. The success rate of the therapy is 55–60 % per one therapeutic cycle.
In approximately one third of women who cannot get pregnant the ovaries are unable to produce eggs capable of fertilization, eventually the ovaries are missing altogether. In such cases, the law of the Czech Republic permits the use of donated oocytes.
For patients who require the IVF cycle with donated oocytes, the Unica Clinic finds a volunteer – a donor who undergoes ovary stimulation instead of the receiving patient and makes the collected oocytes available for the recipient. The oocytes are fertilized using the recipient male partner’s sperm and the resulting embryos are subsequently transferred to the uterus of the recipient – the future mother.
The Unica Clinic has a sufficient number of tested volunteers, thus the treatment can start in the shortest possible time.
Who is the donor?
These are young women, who voluntarily enlist to the assisted reproduction centre and want to help other women. They are mainly students or young mothers on their maternity leaves.
All donors must meet the strict criteria for gamete and embryo donation according to the American Society of Reproductive Medicine (Guidelines for oocyte donation of The American Society of Reproductive Medicine, published in Fertility and Sterility, Vol. 77, No. 6, Suppl. 5, June 2002).
The donors must be below 30 years, free of contagious diseases (HIV, syphilis, jaundice of B and C types, cytomegaloviral infection and Chlamydia). Understandably they must be in good health condition with a pathology-free genetic examination.
Who is the recipient?
a. A woman who does not produce oocytes of sufficient quality This group includes women who underwent IVF treatment repeatedly without acquiring quality eggs, eventually the resulting embryos were not of good quality. In particular, women of higher age can produce oocytes of inferior quality, incapable of fertilization, or the resulting embryos are defective, incapable of perfect development.
b. A women who has no oocytes This group includes women whose ovaries did not develop or whose ovaries were removed surgically, as well as women with premature failure of ovarian reproductive capacity.
c. A woman who is a hereditary disease carrier Genetic examination of these women detected a chromosome defect which could be transferred to the future descendants.